Altered Cellular and Humoral Immunity to Varicella-Zoster Virus in Patients With Autoimmune Diseases
نویسندگان
چکیده
منابع مشابه
Humoral and cellular immunity to varicella-zoster virus: an overview.
Under conditions of naturally acquired primary varicella-zoster virus (VZV) infection, the first response of the naive host is mediated by the innate immune system through antiviral cytokines and the activation of NK cells [1]. These responses are likely to be important for the initial control of VZV at mucosal sites of inoculation and to trigger the induction and amplification of adaptive, VZV...
متن کاملCellular and humoral immune responses to varicella-zoster virus in immunocompromised patients during and after varicella-zoster infections.
Humoral and cell-mediated immune responses to varicella-zoster (V-Z) virus were assessed in patients during and after V-Z infections. Ongoing V-Z infections was associated with minimal cellular immunity but not necessarily with poor humoral immunity. Recovery from V-Z infection was associated with a vigorous cellular immune response. Cell-mediated immunity to V-Z virus was demonstrable for year...
متن کاملCellular immunity to varicella-zoster virus in patients with major depression.
The incidence of herpes zoster increases markedly with advancing age, and this appears to be causally related to an age-dependent decline in varicella-zoster virus (VZV)-specific cellular immunity. Psychologic stress has also been linked to the occurrence of herpes zoster, but the mechanism involved has not been investigated. This study examined the relationship between major depression and VZV...
متن کاملVaricella-zoster virus IE63, a virion component expressed during latency and acute infection, elicits humoral and cellular immunity.
Varicella-zoster virus (VZV) latency in human dorsal root ganglia is characterized by the transcription of large regions of its genome and by the expression of large amounts of some polypeptides, which are also expressed during lytic cycles. The immediate early 63 protein (IE63) is a virion component expressed very early in cutaneous lesions and the first viral protein detected during latency. ...
متن کاملDecreased Immunity to Varicella Zoster Virus in Giant Cell Arteritis
Introduction Herpes zoster, which can have a major impact on quality of life, results from reactivation of a latent varicella zoster virus (VZV) infection. We hypothesized that giant cell arteritis (GCA) patients are at increased risk of herpes zoster because of treatment with high-dose glucocorticoids and advanced age. Aim of the study, therefore, was to determine cell-mediated and humoral imm...
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ژورنال
عنوان ژورنال: Arthritis & Rheumatology
سال: 2014
ISSN: 2326-5191
DOI: 10.1002/art.38804